It's sad she comes off so fucking manly sometimes. If Lohan would stop doing crack, eat a little (even if its rabbit food, at least it would be food), and see psychiatrist she could do this movie.
Seeing as none of those look likely anytime with the next year or two, I'd give it to Jessica or any number of hot celebs that I can think of off the top of my head.
Hell, Emma Watson said she wanted to do a nude scene in an "artsy" movie... Let her play a tormented stripper