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I lived near Stuttgart for a few years, so most of my visits to other German cities have been toward the central and southern regions... Frankfurt, Heidelberg, Augsburg, Ulm, Garmisch, Bertesgaden, etc. Been to Oktoberfest only once though. If you can't go to that festival, then there's the second largest, Cannstatter in Bad Canstatt, right outside of Stuttgart.
Want to study up on places to visit, then I always suggest guides by Rick Steves. He does have a more thorough knowledge on how to travel across Germany and Europe inexpensively.